Xingxing Zang Selected Research

Immune Checkpoint Proteins

1/2022	The immune checkpoint B7x expands tumor-infiltrating Tregs and promotes resistance to anti-CTLA-4 therapy.
1/2020	HHLA2 is expressed in pancreatic and ampullary cancers and increased expression is associated with better post-surgical prognosis.
1/2020	Over-Expression and Prognostic Significance of HHLA2, a New Immune Checkpoint Molecule, in Human Clear Cell Renal Cell Carcinoma.
1/2019	Immune Checkpoint B7x (B7-H4/B7S1/VTCN1) is Over Expressed in Spontaneous Canine Bladder Cancer: The First Report and its Implications in a Preclinical Model.
1/2019	Structures of Immune Checkpoints: An Overview on the CD28-B7 Family.
1/2018	Wide Expression and Significance of Alternative Immune Checkpoint Molecules, B7x and HHLA2, in PD-L1-Negative Human Lung Cancers.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Xingxing Zang Research Topics

Disease

47	Neoplasms (Cancer) 01/2022 - 09/2007
5	Neoplasm Metastasis (Metastasis) 01/2020 - 08/2008
5	Infections 01/2019 - 04/2002
4	Traumatic Brain Injuries (Traumatic Brain Injury) 09/2021 - 01/2018
4	Carcinogenesis 12/2019 - 02/2015
4	Inflammation (Inflammations) 12/2019 - 07/2010
3	Prostatic Neoplasms (Prostate Cancer) 01/2021 - 01/2011
3	Esophageal Squamous Cell Carcinoma 09/2020 - 10/2019
3	Hematologic Neoplasms (Hematological Malignancy) 11/2019 - 01/2016
3	Urinary Bladder Neoplasms (Bladder Cancer) 11/2019 - 01/2017
3	Breast Neoplasms (Breast Cancer) 10/2018 - 10/2012
3	Lung Neoplasms (Lung Cancer) 01/2018 - 01/2016
2	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 01/2020
2	Adult T-Cell Leukemia-Lymphoma (Leukemia Lymphoma, T Cell, Acute, HTLV I Associated) 10/2019 - 01/2019
2	Carcinoma (Carcinomatosis) 10/2018 - 01/2017
2	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2018 - 02/2017
2	Osteosarcoma (Osteogenic Sarcoma) 01/2016 - 01/2016
1	Cytopenia 01/2021
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 01/2021
1	Primitive Neuroectodermal Tumors (PNET) 01/2021
1	Disease Progression 01/2021
1	Multiple Myeloma 01/2021
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2021
1	Pancreatic Neoplasms (Pancreatic Cancer) 01/2020
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2020
1	Lymphoma (Lymphomas) 01/2020
1	Immune System Diseases (Immune Disorders) 12/2019
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 12/2019
1	Spontaneous Abortion (Miscarriage) 12/2019
1	Graft vs Host Disease (Graft-Versus-Host Disease) 12/2019
1	Brain Edema (Cerebral Edema) 11/2019
1	Contusions 11/2019
1	Brain Injuries (Brain Injury) 11/2019
1	Hodgkin Disease (Hodgkin's Disease) 10/2019
1	Lymphatic Metastasis 10/2019
1	Communicable Diseases (Infectious Diseases) 01/2019
1	Hepatocellular Carcinoma (Hepatoma) 01/2019
1	Circulating Neoplastic Cells 01/2019
1	Stomach Neoplasms (Stomach Cancer) 01/2018
1	Brain Diseases (Brain Disorder) 01/2018

Drug/Important Bio-Agent (IBA)

13	Proteins (Proteins, Gene)FDA Link 01/2021 - 04/2013
9	Immune Checkpoint InhibitorsIBA 01/2021 - 01/2016
6	Immune Checkpoint ProteinsIBA 01/2022 - 01/2018
6	LigandsIBA 01/2021 - 01/2011
5	Monoclonal AntibodiesIBA 11/2019 - 01/2011
4	AntibodiesIBA 02/2017 - 04/2002
3	Interleukin-6 (Interleukin 6)IBA 01/2021 - 08/2013
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2021 - 02/2014
3	Chimeric Antigen ReceptorsIBA 01/2021 - 01/2016
3	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2017
3	Programmed Cell Death 1 ReceptorIBA 01/2021 - 01/2011
3	AntigensIBA 11/2019 - 08/2013
2	Tripartite Motif ProteinsIBA 09/2021 - 11/2019
2	B7-H1 AntigenIBA 01/2021 - 01/2016
2	Nicotinamide N-MethyltransferaseIBA 09/2020 - 10/2019
2	CateninsIBA 09/2020 - 10/2019
2	Small Interfering RNA (siRNA)IBA 01/2020 - 01/2019
2	RNA (Ribonucleic Acid)IBA 01/2019 - 01/2019
2	Neuroprotective AgentsIBA 01/2019 - 01/2018
2	Interleukin-10 (Interleukin 10)IBA 10/2017 - 01/2016
2	CytokinesIBA 10/2017 - 04/2013
2	VaccinesIBA 08/2013 - 06/2013
2	Immunoglobulin G (IgG)IBA 07/2005 - 04/2002
1	axicabtagene ciloleucelIBA 01/2021
1	Hypoxia-Inducible Factor 1IBA 01/2021
1	Immunologic Factors (Immunomodulators)IBA 01/2020
1	Biological ProductsIBA 01/2020
1	Histone Deacetylase InhibitorsIBA 01/2020
1	Neutralizing AntibodiesIBA 01/2020
1	Messenger RNA (mRNA)IBA 01/2020
1	entinostat (MS 275)IBA 12/2019
1	LipopolysaccharidesIBA 12/2019
1	Histone Deacetylases (Histone Deacetylase)IBA 12/2019
1	Concanavalin AIBA 12/2019
1	Galectins (Galectin)IBA 11/2019
1	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2019
1	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 11/2019
1	NivolumabIBA 10/2019
1	N-nitroso-N-methyltyramine (NNMT)IBA 10/2019
1	Mucin-3IBA 01/2019
1	p21-Activated KinasesIBA 01/2019
1	Fibronectins (Fibronectin)IBA 01/2019
1	CholesterolIBA 01/2019
1	Immunoglobulins (Immunoglobulin)IBA 01/2019
1	Protein Isoforms (Isoforms)IBA 01/2019
1	IntegrinsIBA 01/2019
1	PF 3758309IBA 01/2019
1	Cadherins (E-Cadherin)IBA 01/2019
1	Transcription Factors (Transcription Factor)IBA 01/2018
1	Histone Deacetylase 1IBA 01/2018
1	Neuropilin-1IBA 10/2017

Therapy/Procedure

20	Therapeutics 01/2022 - 09/2007
20	Immunotherapy 01/2022 - 09/2007
2	Transplantation 01/2019 - 01/2017
2	Drug Therapy (Chemotherapy) 01/2016 - 10/2012
1	Induced Abortion (Induced Abortions) 12/2019
1	Intravenous Administration 11/2019
1	Castration 01/2019
1	Neoadjuvant Therapy 10/2018
1	Stem Cell Transplantation 01/2018